To investigate the clinical effect of Shensongyangxin capsule combined with western medicine in treating patients with heart failure and ventricular arrhythmia and its effects on N plasma N-terminal pro brain natriuretic peptide (NT-proBNP) and ECG QT dispersion (QTd). Methods:From January 2014 to April 2016， 96 patients with heart failure and ventricular arrhythmia in the department of cardiology of our hospital were divided into western medicine group and traditional Chinese medicine combined with western medicine group according to the number of visits， with 48 cases in each group. All patients were given amiodarone， and patients in the traditional Chinese medicine combined with western medicine group were also given Shensongyangxin capsule. After two months’ treatment， the clinical effect of two groups were compared. Results:After treatment， the dynamic electrocardiograph (ECG) beats， beats frequency， plasma NT-proBNP and QTd in ECG of traditional Chinese medicine combined with western medicine group were lower than those of the western medicine group (P<0.05). In the former group， the premature ventricular Lown grading was better than that of the latter(P<0.05); after treatment， the curative rate in the former (64.58%) was higher than that of the latter (43.75%) (P<0.05). Conclusion:The curative effects of Shensongyangxin capsule combined with arrhythmia is better than single western medicine. Western medicine combined with Shensongyangxin capsule can significantly reduce the plasma levels of NT-proBNP and QTd in ECG.