Pulse pressure is an important independent risk factor for cardiovascular and cerebrovascular disease and has become a hotspot in the field. Numerous clinical studies have shown that pulse pressure is not only associated with coronary heart disease，cardiac hypertrophy，heart failure，arrhythmia，atherosclerosis，but also closely related to cerebral vascular disease and renal damage. Although not mentioned in ancient traditional Chinese medicine books of，TCM researches on pulse pressure constantly has been carried out in recent years，mainly focusing on kidney deficiency，blood stasis and phlegm dampness and so on. The medication principle is for tonifying kidney and activating blood circulation，removing blood stasis and dredging collateral or eliminating dampness and resolving phlegm. Reviewing the research progress of both traditional Chinese and Western medicine on pulse pressure，this paper is to provide ideas and platform for more extensive，deep，detailed and long-term studies in the future.