In recent years, the development of Traditional Chinese Medicine （TCM） has become increasingly important, but it still needs to be strengthened in the aspects of the recognition of Western Medicine and high-quality treatment research. This paper discussed research bias and evidence of TCM in the perspective of Evidence-based Medicine, presented the grading factors of the quality of evidence and the strength of recommendation in area of TCM. It is expected to improve the production and application of evidence in TCM through the primary studies, systematic reviews and practice guidelines.