Abstract:To summarize and evaluate the evidence of non-pharmacological intervention of Traditional Chinese Medical in Alzheimer’s disease (AD) and provide supports. Methods:A systematic literature search was performed. CNKI, Wanfang, Pubmed, Medline, Cochrane library, Embase, PsycINFO, CINAHL, CQVIP, ACP Journal Club(www.acpjc.org ) were searched for related systematic reviews. The methodological quality and the quality of the evidences were evaluated using the Assessment of Multiple Systematic Reviews (AMSTAR) and Grading of Recommendations Assessment, Development and Evaluation (GRADE) approaches. The guideline was evaluated using AGREE II.Results:Seven systematic reviews and meta-analyses of acupuncture for AD were included, one of aromatherapy and one of non-pharmacological intervention for AD, four of massage (included one article of acu-point massage). The compliance with AMSTAR checklist items regarding to acupuncture systematic reviews ranged from 6.5 to 11. The quality of the bodies of evidence of acupuncture we assessed ranged from very low to moderate, and no high quality bodies of evidence were found. The effectiveness of aromatherapy for agitation or behavior symptom of AD remained inconclusive. Acu-point massage revealed positive effective in controlling psychological or behavior symptoms.Conclusion:There is still expectations for more researches including primary and secondary literature about non-pharmacological intervention of TCM for AD. The overall quality of the evidence remains sub-optimal which raises concerns regarding their roles in clinical practice. Thus, the conclusions in reviews must be treated with caution and their roles in clinical practice should be limited.