To observe the clinical effect of Jiuwei Dihuang decoction combined with body constitution differentiation in the treatment of senile vaginitis. Methods:A total of 90 senile vaginitis patients admitted into our hospital from January 2014 to April 2016 were randomly divided into dialectical treatment group and control group with 45 cases in each. Patients in both groups were treated with Baofukang Suppository, on this basis, the treatment group was treated with Liuwei Dihuang decoction according to different body constitution. To treat for 2 courses （30 days for 1 course） and observe the clinical efficacy of the two groups. Results:After treatment, dialectical leucorrhea vulva pruritus, leucorrhea, vaginal abnormal smell, sexual intercourse pain scores of the treatment group were lower than those of the control group, and the differences were statistically significant （P<0.05）. Vaginal elasticity, vaginal moist, vaginal mucosa, vaginal pH dialectical vaginal cleanliness scores of the treatment group were lower than those of the control group, and the difference was with statistical significance （P<0.05）. After treatment, the curative rate of the treatment group is 66.67%, marked effective rate 24.44%, effective rate 8.89% and ineffective rate 0%. However, curative effect of the control group is 44.44%, marked effective rate 15.56%, effective rate 26.67%, and ineffective rate 2.22%. The differences were statistically significant（P<0.05）. Conclusion:Liuwei Dihuang decoction combined with body constitution therapy is effective in treating senile vaginitis.