To observe the difference in the clinical efficacy on insomnia among the intervention of one side ear-embeding therapy,two side ear-embeding therapy and conventional acupuncture methods and verify the effectiveness and safety of ear-embeding therapy.Methods:Sixty cases of insomnia were randomized into an one side ear-embeding group（20 cases）,a two side ear-embeding group（20 cases）and a regular acupuncture group（20 cases）.In the ear-embeding group,Shenmen,Jiaogan,Pizhixia,Xin were selected with ear-embeding.One side ear-embeding group was treated by two ears alternately and each ear was treated 3 days.Two side ear-embeding group was treated by both two ears for 6 days and rested 1 day.In the conventional acupuncture group,Baihui,Anmian,Shenmai,Zhaohai,Shenmen,Sanyinjiao as main point were punctured withweek,4 weeks made one session.The scores of PSQI and ESS before and after treatment were observed in three groups.Results:PSQI and ESS scores were reduced after treatment in every group（both P<0.01），and three group had the same efficacy（P>0.05）.Conclusion:The one side ear-embeding therapy is safe and effective in the treatment of insomnia and achieves the same efficacy as the two side ear-embeding therapy and conventional acupuncture.The operability,safety and patient compliance of one side ear-embeding are better than that of two side ear-embeding and conventional acupuncture.