To investigate the effect of massage combined with continuous ice on rehabilitation and prevention of deep vein thrombosis （DVT） in patients with total knee arthroplasty （TKA）.Methods:A total of 98 patients with osteoarthritis were treated with TKA,control group （n=49） was given routinely perioperative drug therapy and continuous passive exercise training,The observation group （n=49） was simultaneously punched with continuous ice.The changes of coagulation function before and after operation were detected and compared,the knee function and the degree of pain were evaluated,the peak wave velocity and mean velocity of 2 groups were measured,DVT occurrences was statisticsed.Results:Compared with preoperative,D-D and FIB increased first and then decreased,and PT and APTT decreased first and then increased （P<0.05 or P<0.01）; the levels of FIB,PT and APTT in observation group 14 days after surgery were basically restored to preoperative （P>0.05）.Compared with preoperative,the excellent rate of knee function was gradually increasing from 3 months to 6 months after operation （P<0.01）,and the excellent rate of observation group was significantly higher than that of control group （P<0.05）..The peak and mean velocity of femoral vein blood flow were significantly higher than those before operation,and the observation group was significantly higher than the control group （P<0.01）.The VAS score of 3 d and 14 d after surgery were significantly lower than those of control group （P<0.01）.The incidence of DVT in observation group was significantly lower than that in control group （18.37%） （P<0.05）.Conclusion:TKA postoperative massage with continuous ice can effectively promote postoperative knee function recovery,prevention of DVT formation,reduce the degree of postoperative pain,the effect is significant.