To explore the prevention and treatment of diabetes from traditional Chinese medicine by combining modern clinical practice with classics of traditional Chinese medicine.Methods:Deeply study classics of traditional Chinese medicine and combine it with the clinical practice to explore the whole evolution process of diabetes，and then try to find out corresponding theoretical foundation as well as therapy and formula.Results:A total of 11 items summed up all of the following:the meaning of consumptive thirst，cause and mechanism of disease，syndrome and therapy，original and innovative prescriptions，syndrome change and therapy change，and formed differentiation of modern Chinese medicine item by item.Conclusion:It was returning back the method of studying classics of traditional Chinese medicine and developing syndrome differentiation that fit clinic and are benefit for classics inheritance.And the center is to innovate.