To observe the clinical efficacy of Yiqi Yangyin Huoxue Decoction in treating qi and yin deficiency and blood stasis in patients with early stage-type 2 diabetic nephropathy. Methods:A total of 60 patients with early stage-type 2 diabetic nephropathy were randomly divided into two groups:treatment group and control group. Observe the effect of Yiqi Yangyin Huoxue decoction on blood glucose, mALB, mALB/Ucr and clinical symptoms in patients with qi and yin deficiency and blood stasis of early stage-type 2 diabetic nephropathy. Comparison with the control group was made. Results:After treatment, mALB and mALB/Ucr in the two groups were significantly decreased（P<0.05）; and the two groups were significantly different in terms of mALB/Ucr and mALB（P<0.05）, with the blood glucose significantly decreased in the treatment group（P<0.05）.The Clinical symptoms were improved. Conclusion: There is positive significance in Yiqi Yangyin Huoxue decoction in the treatment of early stage-type 2 diabetic nephropathy by reducing mALB, mALB/Ucr,and blood sugar, thereby improving the clinical symptoms.