To investigate the efficacy and safety of Invigorating-spleen and Ventilating-lung Therapy Combined with Budesonide atomized inhalation in the Treatment of Pediatric Chronic Cough.Methods:Eighty-six children with chronic cough were divided into study group and control group, with 43 cases in each group. Both patients in the control and study group were treated with budesonide atomized inhalation therapy, while the study group was additionally treated by Invigorating-spleen and Ventilating-lung Therapy. The changes in clinical symptoms and adverse reactions were observed. TCM symptom score was used to evaluate the change of clinical symptoms. Chester Cough Questionnaire (LCQ) was used to evaluate the quality of life.Results:The efficacy of the study group was significantly better than that of the control group. The difference was statistically significant (P<0.05). Cough and night cough, expectoration, shortness of breath, wheezing, chest tightness and total symptom score of the two groups after the treatment decreased significantly (P<0.05) and those of the study group were significantly lower with statistically significant difference (P<0.05). The mental health, physical health, social function and total score of the two groups increased significantly after the treatment (P<0.05), but the study group were significantly higher, showing that the difference was statistically significant (P<0.05). During the treatment, there was no obvious adverse reaction in the two groups.Conclusion:Invigorating-spleen and Ventilating-lung Therapy combined with budesonide atomized inhalation can significantly improve the clinical symptoms of chronic cough in children and improve the quality of life.