To observe the curative effect of Garlicin capsules combined with Kangfuxin liquid in the treatment of recurrent oral ulcer.Methods:Ninty-three cases of recurrent oral ulcer were randomly selected from January 2016 to August in our hospital, then were divided into treatment group and control group, respectively 46 and 47 cases.The treatment group was given Garlicin capsules combined with Kangfuxin liquid and the control group were treated with Kangfuxin liquid sorely.Treatment course lasts for 7 days, and to perform two courses.Observe salivary epidermal growth factor (EGF) levels of T lymphocyte subsets level, ulcer pain duration and ulcer healing time of the two groups and compare the clinical effect.Results:After two courses of treatment, salivary epidermal growth factor in saliva EGF concentration in the treatment and control group are (2.86±0.41)ng/mL, (3.85±0.51)ng/mL, serum alpha TNF-respectively (37.71±5.24)pg/mL, (52.64±11.14)pg/mL.The treatment group performs better than the control group, and the difference was statistically significant (P<0.05).In the treatment group, T lymphocyte subsets value are D3 (82.56±13.47)%, CD4 (46.71±5.84)%, CD8 (24.41±2.85)%, CD4/CD8 (1.83±0.55)%, and in the control group, T lymphocyte subsets are D3 (73.75±9.26)%, CD4 (32.64±4.14)%, CD8 (26.78±2.96)%, CD4/CD8 (1.52±0.53)%.The treatment group performs better than the control group, and the difference was statistically significant (P<0.05).The treatment group’s ulcer pain duration and ulcer healing time was (3.68±0.95）d, (3.22±0.69）d, and those are (5.78±1.37）d, (5.47±1.61)d in the control group.The treatment group performs better than the control group, and the difference was statistically significant (P<0.05).Effective rate in the control group and treatment group were 84.7% and 97.8% respectively, and the treatment group performs better than the control group with statistically significantce (P<0.05).Conclusion:The curative effect of Garlicin capsules combined with Kangfuxin liquid in treatment of recurrent oral ulcer is significant.It can promote ulcer healing process, enhance immune function, of high safety and is worthy of clinical promotion.