To investigate the effect of acupuncture combined with low-temperature impact and rehabilitation training on cervical muscle fibrosis and quality of life in patients with nasopharyngeal carcinoma (NPC) after radiotherapy.Methods:Fifty-two patients with NPC radiotherapy from January 2016 to December 2016 were selected as the subjects and were divided into control group and observation group according to their treatment. The patients in the control group received conventional treatment with low-temperature impact and rehabilitation training. Patients in the observation group were additionally treated with acupuncture. All the patients received 4-week treatment. The occurrence of the maximal muscle fibrosis, quality of life, and other complications were compared between the two groups after the treatment.Results:1) The degree of muscle fibrosis in the neck of the observation group was significantly better than that in the control group (P<0.05); 2) The quality of life of the observation group was significantly higher than that of the control group (P<0.05). 3) The incidence of complications (15.38%) in the observation group was significantly lower than that in the control group (38.46%), with statistically significant difference (P<0.05).Conclusion:Acupuncture combined with low-temperature impact and rehabilitation training may significantly improve muscle fibrosis and the quality of life of patients with nasopharyngeal carcinoma after radiotherapy, which can be used as a clinical treatment for patients with NPC after radiotherapy.