To investigate the acupuncture intervention muscle spasm in patients receiving hemodialysis and the effect of tic.Methods:One-hundred and twenty cases of hemodialysis patients who were treated in the hospital during March 2015-January 2017 were selected and randomly divided into observation group (acupuncture group) with 60 cases and control group (conventional treatment group) with 60 cases. The clinical efficacy of the two groups was compared.Results:The on-the-spot curative effect of observation group was better than control group, observation group of patients obviously relieve muscle spasm and tics, compared two groups have statistical significance (P<0.05).Conclusion:Patient’s clinical symptoms may significantly relieve after acupuncture intervention treatment. It may also reduce the conventional western medicine used for muscle spasms and convulsion drugs and avoid side effects.