To observe the clinical effect of mifepristone combined with Xiaojin Capsule in the treatment of endometriosis.Methods:A total of 120 patients diagnosed as uterine fibroids were randomized divided into 2 groups.The control group (60 patients) were treated with Mifepristone, and the treatment group (60 patients) were added Xiaojin capsule.The effective rate, the levels of CA125, the levels of sex hormone, recurrence rate and adverse reaction of two groups after continuous 6 months' treatment were observed.Results:The total effective rate of treatment group was significantly higher than that of control group (P<0 05), and the levels of CA125 and recurrence rate were lower than that of control group.There was no significant difference in the levels of sex hormone (P>0.05).There were no significant difference in sex hormone levels of two groups (P>0.05).Conclusion:Mifepristone combined with Xiaojin capsule is effective for patients with endometriosis, which is worthy of clinical promotion.