To observe the clinical effect of percutaneous kyphoplast (PKP) and Chinese patent medicine in the treatment of senile patients with old osteoporotic vertebral compression fractures.Methods:A total of 40 senile patients with old osteoporotic vertebral compression fractures who were admitted and treated in Qinhuangdao Orthopedic Hospital from February 2014 to February 2017 were selected and divided into control group and observation group, with 20 cases in each group.The control group was treated with PKP method, while the observation group was added Shangke Jiegu Tablet.Visual analogue scale (VAS), Oswestry dysfunction index score (ODI) and vertebral height compression of two groups were compared.Results:After treatment, the VAS score and ODI score of the two groups were significantly lower than that before treatment, and the difference was statistically significant (P<0.05).And that of observation group was significantly lower than that of control group (P<0.05).The recovery rate of vertebral body height of the two groups was significantly higher than that before treatment, and the difference was statistically significant (P<0.05), but there was no significant difference between the two groups (P>0.05).Conclusion:PKP with Chinese patent medicine in the treatment of senile patients with old osteoporotic vertebral compression fractures is effective, not only in pain relief, but can also improve the dysfunction of lumbar vertebra, with good recovery rate of vertebral body height