Radix Arnebiae is an important herb of TCM dermatology.The article combed the change of its processing methods of Radix Arnebiae and reviewed the research development of the effective component extraction and the clinical application of Radix Arnebiae oil and Radix Arnebiae ointment, to summarize the application of Radix Arnebiae in dermatology, and broaden clinical thought.The article also pointed that combination of agriculture, pharmaceutical engineering and clinical medicine and the combination of modern effective component extraction technique and traditional processing would become an important driving force to promote the future development and reform of TCM.