Psoriasis belongs to the category of “Baibi” in traditional Chinese medicine(TCM).It is a common,chronic and recurrent,erythema,desquamation,plaque lesions of skin disease and the course of disease is lingering and repeated,intractable.As a kind of common disease in clinic,it is difficult to cure.The etiology and pathogenesis of psoriasis can be explained by blood heat theory,blood stasis theory and blood dryness theory.TCM treatment of psoriasis mainly focus on clearing heat and detoxification,activating blood and remove stasis,as well as nourishing blood and yin.Core medicine used are mainly blood regulating medicine.In this paper,the mechanism of using blood regulating medicine,the common medicine used as well as their effects will be introduced.