To investigate the effects of electro-acupuncture(EA) combined with local anesthesia or general anesthesia on intraoperative anesthesia maintenance and post-operative recovery in cerebral artery stenting patients.Methods:A total of 165 cases from December 2015 to October 2016 were assigned into local anesthesia and electro-acupuncture group (group LA，n=41)，local anesthesia control group (group LC，n=44)，general anesthesia and electro-acupuncture group (group GA，n=38)，general anesthesia control group (group GC，n=42).The patients in Group LA and GA received EA at acupoints of Shuigou (GV 26) and Baihui (GV 20)，Hegu (LI 4) and Waiguan (TE 5) at the same side of the stenting.The patients in group LA and group GA were received EA，while patients in group LC and group GC were received shame EA.The change of MAP，the use of vasoactive drugs and anesthetics during the four groups，post-operative pain scores (visual analogue scale，VAS) and the recovery condition after operation were recorded and analyzed.Results:Basic conditions showed that patients who use general anesthesia presented with vertebrobasilar occlusion stroke，whereas local anesthesia usually used in patients presenting with anterior circulation stroke (GC=28 cases，GA=29 cases).The average use of nimodipine in group LA was significantly less than group LC (P<0.05).The average use of dopamine in group GA was significantly less than group GC (P<0.05).The use of remifentanil in group GA was less than group GC (P<0.05).The time of postoperative respiratory recovery，wake-up and extraction in group GA were much less than the GC group (P<0.01).At 9 am and 4 pm 1 day after operation，the number of patient with pain (VAS≥4) in group LA was smaller than group LC (P<0.05)，and group GA was smaller than group GC (P<0.05).Conclusion:The selection of anesthesia methods was closely related with location of vascular occlusion.EA combined with local anesthesia or general anesthesia in CAS could stabilize hemodynamics，decrease the use of vasoactive agent and anesthetics，with effects of supplementary analgesic and improving anesthesia recovery，which is worthy of clinical promotion.