Effects of Radix et Rhizoma Salviae Miltiorrhiza Adjuvant Therapy on Neonatal Pneumonia Patients' Lung Function,Blood Coagulation and Platelet Parameters
To investigate the effects of Radix et Rhizoma Salviae Miltiorrhiza adjuvant therapy on neonatal pneumonia patients' lung function,blood coagulation and platelet parameters.Methods:A total of 160 patients with neonatal pneumonia who were admitted and treatment in our hospital from September 2012 to October 2015 were selected.By using lot method,all patients were randomly divided into control group and Radix et Rhizoma Salviae Miltiorrhiza group (salvia group),with 80 patients in each group.The patients of control group were received conventional anti-infection treatment and the patients of salvia group were added salvia adjuvant therapy based on conventional treatment.The lung function,blood coagulation and platelet parameters of all patients before and after treatment were detected.Results:As for lung function,6 indicators were significant improved (P<0.05) and 3 indicators had improved but not significantly (P>0.05) in control group.Otherwise,all indicators showed significant improvment (P<0.05) compared with pre-treatment in salvia group,which had better effect than control group.As for blood coagulation function,the activated partial thromboplastin time (APTT),prothrombin time (PT) and thrombin time (TT) decreased significantly compared with pretreatment (P<0.05),and the concentration of fibrinogen (FIB) increased but the difference was not significant (P>0.05) in control group.However,the difference of APTT,PT,TT and FIB pre/pro-treatment in salvia group were all statistically significant (P<0.05),especially the level of APTT,PT and TT in salvia group were significantly decreased (P<0.05) compared with control group,and FIB also improved more significantly.As for platelet parameters,both groups were improved significantly (P<0.05) compared with pretreatment and salvia group showed better improving effect than control group.Conclusion:Salvia adjuvant therapy can significantly improve the neonatal pneumonia patients' lung function,blood coagulation and platelet parameters compared with conventional treatment,which is both economic and effective and worthy of clinical promotion.