To study the curative effects of Maxing Erchen Sanzi Decoction on children with acute episode of bronchial asthma and its influence on immune mechanism.Methods:A total of 90 children with acute episode of bronchial asthma who were treated in our hospital from August 2014 to December 2016 were selected and randomly divided into control group and observation group with 45 cases in each group according to random number table.Patients in control group were treated with routine treatment，and those in observation group were added Maxing Erchen Sanzi Decoction.The curative effects，the differences of Th17/Treg cell immunity and Th1/Th2 cell immunity between two groups were compared.Results:After treatment，the total efficiency in observation group was higher than that in control group (P<0.05); The peripheral blood Th17 cell proportion and Th17/Treg ratio in observation group were lower than that in control group，and the proportion of Treg cells was higher than that in control group (P<0.05); serum contents of Th1 cell factors such as IL-2 IFN-γwere higher than those in control group，and contents of Th2 cytokines such as IL-4，IL-10 were lower than those in control group (P<0.05).Conclusion:Maxing Erchen Sanzi Decoction treatment in children with acute episode of bronchial asthma can effectively improve the overall curative effects，and optimize the immune function.