To assess Bushenzhuangjin Decoction for orthopaedics clinical application from evidence-based medicine. Methods:According to the computer-based online search, articles of PubMed, Embase, Medline, Cochrane Library, CBM, CNKI, Wanfang Database and VIP published before May lst，2016 were searched for Bushen Zhuangjin Decoction in orthopaedics clinical application．Seven studies were abstracted and synthesized by ReviewManager 5.3 for Meta-analysis. Results:Compared with positive control group, Bushenzhuangjin decoction had equal outcome for osteoarthritis at early stage follow-up ［RR=1.07；95%CI:(0.99，1.15)，P=0.09］. However, Bushenzhuangjin decoction had better outcome than positive control group at early stage follow-up ［RR=1.33；95%CI:(1.19，1.50)，P<0.00001］. Conclusion:Bushenzhuangjin Decoction had advantage in treatment of orthopedic diseases. However, because of limition of the RCTs, the result of this study can be deviation. Therefore, more qualitified researches with large sample were expected to evaluate these resaults.