To explore the curative effect of gynecological Qianjin pills combined with Chinese materia medica enema in the treatment of patients with chronic pelvic inflammatory disease and its influence on hemorheology and inflammatory factors. Methods:A total of 108 cases patients with chronic pelvic inflammatory disease were selected and randomly divided into the treatment group and the control group with 54 cases in each group. The control group was treated with conventional treatment, and the treatment group was treated with gynecological Qianjin pills on the basis of the control group. The 2 groups were treated continuously for 14 d. The clinical efficacy of the 2 groups was evaluated, and the changes of hemorheological indexes, inflammatory factors and quality of life in the 2 groups were detected and compared. Results:The total efficiency of the treatment group was 96.30%, which was significantly higher than 85.19% of the control group (P<0.05); the 2 groups after treatment, whole blood high and low shear viscosity, plasma viscosity, erythrocyte aggregation index and fibrinogen were significantly lower than before treatment (P<0.05 or P<0.01), and the treatment group was significantly lower than the control group (P<0.05 or P<0.01); after treatment, levels of IL-2 in the 2 groups increased significantly, and levels of CRP, TNF-α and quality of life scores were significantly lower than before treatment (P<0.01), and the difference between the 2 groups was significant (P<0.05 or P<0.01). Conclusion:The curative effect of gynecological Qianjin pills combined with chinese medicine enema in the treatment of patients with chronic pelvic inflammatory disease is accurate, which can effectively reduce the levels of inflammatory factors, improve the high viscosity state of blood, and improve the quality of life.