To investigate the clinical effects of modified Xiao Qinglong Decoction in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Methods:From February 2013 to February 2016,a total of 180 AECOPD patients in our hospital were selected and divided into observation group and control group with 90 cases in each.The control group was treated with conventional western medicine,and the observation group was givenXiao Qinglong Decoction based on the treatment of the control group.With 10 d as a a course of treatment in the two groups,to observe for 3 courses.Results:The total effective rate of the observation group and the control group were 95.6% and 84.4% respectively.The total effective rate of the observation group was significantly higher than that of the control group (P<0.05).In the observation group and control group after treatment,the contents of CD4+ cells were 36.34±7.83% and 33.66±9.82%,respectively that were significantly higher than before treatment of 30.33±6.49% and 30.49±5.33% (P<0.05),and the observation group was significantly higher than that of the control group (P<0.05).After treatment,the FEV1 and FEV1/FVC values in the observation group and the control group were higher than before treatment (P<0.05),while the FEV1 and FEV1/FVC values of the observation group were significantly higher than those in the control group (P<0.05).The serum IL-6 and TNF-α values in the observation group and control group after treatment were significantly lower than before treatment (P<0.05),while the serum IL-6 and TNF-α values in the observation group after treatment were significantly lower than the control group (P<0.05).Conclusion:Xiao Qinglong Decoction in the treatment of patients with AECOPD can take comprehensive effect by improving respiratory muscle function,regulating the body's immune function,regulating the release of inflammatory factors,and it can improve the treatment effect.