Abstract:To investigate the effect of purple cabbage extract (PCE) on breast cancer cell MCF7 growth and migration.Methods:The inhibition rate of MCF7 cells was assessed by MTT method,and the inverted phase contrast microscope was used to observe the cellular shape.Flow cytometry was utilized for measuring cell apoptosis after Annexin V-FITC/PI stained the cell.The transwell chamber was used to investigate cell migration.Results:PCE inhibited MCF7 cell proliferation in a concentration-and time-dependent manner (P<0.05).After incubated with PCE,the cells became shrinkage and turned round,arranged loosely and adhered not favorable gradually.PCE induced MCF7 cell apoptosis and inhibited cell migration in a concentration-dependent manner (P<0.05).Conclusion:PCE inhibits breast cancer cell MCF7 growth and migration.