To explore the law of treatment of labor malaria and provide treatment ideas for malaria in clinical practice, so as to obtain good clinical curative effects. Methods:The data of malaria cases in the bibliography of Collection of Medical Cases was used to establish the database. The recorded medical records were indexed from the aspects of symptoms and medication, and the statistical frequency counting method was used for statistical analysis. Results:Clinical manifestations of malaria were both seen with malaria symptoms of fever, headache, sweating and deficiency symptoms of thin, fatigue, weak pulse. The most frequently used medications were Radix Ginseng, Radix Angelicae Sinensis and Pericarpium Cirri Reticulatae. A large number of tonic drugs were used, while tranquilizers were less used. In 28 medical records, 5 cases clearly pointed out that the use of Buzhong Yiqi Decoction was used to treat malaria. Conclusion:The treatment of malaria should be based on boosting qi and nourishing blood, accompanying with dispelling evil and cutting malaria. Buzhong Yiqi Decoction has an important significance in the treatment of malaria labor.