To evaluate the efficacy of Chinese medicine Jinghua Weikang Pills combined with proton pump inhibitors and antibiotics in the treatment of Hp-Positive peptic ulcer and provide reference for medication.Methods:Related literatures were searched through PubMed,VIP Information and Wanfang Data,and analyzed by RevMan 5.3 software.Results:According to the inclusion and exclusion criteria,a total of 18 literatures were included in the study,involving a total of 2 177 therapists.The results of meta-analysis showed: The total effective rate of the experimental group was better than that of the control group (OR=6.35,95%CI(4.05,9.93),P<0.05).The curative rate of helicobacter pylori in the experimental group was better than that of the control group (OR=3.41,95% CI (2.63,4.41),P<0.05).The healing rate of ulcer in the experimental group was better than that of the control group (OR=2.82,95%CI (2.14,3.71),P<0.05).Conclusion:Experimental group in the treatment of Hp-positive Peptic Ulcer is better than that of the control group.