IgA nephropathy is a special immune type of primary glomerulonephritis,characterized by mesangial IgA deposition.The development of IgA nephropathy is related to immune-inflammatory response,renal fibrosis,podocyte fibrosis and podocyte injury,et al.The mechanism of treatment of IgA nephropathy with traditional Chinese medicine was not clear.However,innovation and improvement of animal model has provided conditions for following research of IgA nephropathy.