To explore the curative effect of integrated traditional Chinese and Western Medicine on sleep disorders in patients with Parkinson disease. Methods:According to the case number and the random number table, 120 patients with Parkinson sleep disorder were randomly divided into two groups, with 60 cases in each group. Two groups were given Parkinson conventional treatment of western medicine. The control group was treated with conventional therapy based on zopiclone 7.5 mg, oral administration, qn. The observation group on the basis of conventional treatment was given Bushen Dingchan Anshen Fang. The two groups were treated for 21 days. After treatment, the clinical efficacy, PSQI scale score and adverse reactions were observed. Results:The PSQI score of two groups after treatment was lower than that before treatment (P<0.05). After treatment, PSQI scores of the observation group were significantly lower than the control group after treatment (P<0.05). After treatment the total clinical efficiency (93.4%) in the observation group was significantly higher than the control group (63.3%) (P<0.01). All kinds of adverse reaction rate in the observation group was lower than the control group, (P<0.01). Conclusion:The combination of traditional Chinese medicine and Western medicine can effectively reduce the PSQI scale score of patients with Parkinson sleep disorder, improve the clinical efficacy and reduce the incidence of adverse reactions.