Allergic disease refers to a kind of disease caused by abnormal reaction of human immune system under the interference of internal and external factors. According to the World Health Organization (WHO) survey, 22% to 25% people in the world are suffering from allergic diseases, and it is increasing 23 times every 10 years, so is the incidence increasing in China. Therefore, the allergy and antiallergic issues have gained much more attention. In the last century, “Guomin Decoction” was developed by Chinese medicine field, providing ideas and methods for clinical treatment of allergic diseases. This paper analyzed the experience and understanding of the treatment of allergic diseases based on the application of dGuomin Decoction” in this studio, and proposed the combination of disease and pattern, and the combination of treatment based on disease differentiation and treatment based on pattern differentiation. Both combinations are beneficial to the clinical application and the improvement of the curative effect of Chinese Medicine. The analysis is shared together with fellow colleagues, and contributes to the clinical application and development of Chinese Medicine.