To observe the clinical efficacy of massage and application on the children with persistent and chronic diarrhea, and to observe the improvement about the accompanying symptoms of indigestion. By measuring the stool pH value, the contents of reducing sugar and fat, to determine the intervention effect of massage and application on poor digestive absorption of fat and lactose of children with chronic diarrhea. Methods:A total of 150 cases of children with chronic diarrhea who were treated in outpatient department of pediatric in our hospital were collected and divided into control group and treatment group, with 75 cases in each group. In the treatment group, 38 cases were collected and they at least met one of three following conditions. Fecal fat was selected with visible fat drops, and reducing sugar was larger than ++, fecal pH value＜6.9 or>7.2. The faeces before and after the treatment was collected respectively, and the fecal pH value, number of fat drops after sultan staining by microscopic examination were determined. Lead acetate method was used for the determination of reducing sugar qualitative. The changes of the above 3 indicators before and after treatment were compared. Results:The total effective rate in treatment group was 100%, significantly higher than that in control group; In the treatment group, symptom integral in the aspects of stool property, abdominal distension, loss of appetite and food intake was significantly better than the control group; The fecal pH value of 38 children was between 5.5 to 7.0 before and after treatment, and the fecal pH value increased was slightly increased. The difference was statistically significant (P<0.05); 22 cases children faeces were found fat drops before treatment, and the result was better after treatment. The difference was statistically significant (P<0.05); And sugar qualitative of 21 cases was larger than 2+, and significantly improved after treatment. The difference was statistically significant (P<0.05). Conclusion:Massage and application treatment of pediatric chronic diarrhea is an effective method, which can significantly improve stool property in children with chronic diarrhea, and promote the function of the digestion and absorption. The treatment of massage and application can reduce the number of fecal fat drops, reduce sugar content in feces, and also it can promote the function of the digestion and absorption in fat and carbohydrates, contributes to the recovery of lactose intolerance, plays a role in invigorating the spleen to arrest diarrhea.