To investigate the clinical effects of Shenqi Dihuang powder on acute renal injury and its effects on renal function.Methods:A total of 82 cases of acute renal injury admitted in Weifang Hospital of Traditional Chinese Medicine from October 2015 to October 2016 were divided into observation group of 41 cases and control group of 41 cases according to the random number table method.The control group was treated with conventional western medicine, while the observation group was treated with Shenqi Dihuang powder on the basis of the control group.The two groups were treated for 8 weeks.The therapeutic effects of the two groups were compared, and the changes of Cys C, UAER and adverse reactions were observed before and after treatment.Results:The total efficiency of the observation group (90.24%) was higher than the control group (68.29%)(P<0.05); Serum Scr and BUN decreased after treatment in 2 groups (P<0.05); After treatment, serum Scr and BUN were lower in the observation group than the control group (P<0.05); the serum Cys C decreased after treatment in 2 groups (P<0.05); After treatment, serum Cys C level in observation group was lower than the control group (P<0.05); the content of UAER decreased in 2 groups after treatment (P<0.05); After treatment, UAER in observation group was lower than the control group (P<0.05); No serious adverse reactions occurred in 2 groups.Conclusion:The clinical efficacy of Shenqi Dihuang powder in the treatment of acute kidney injury is significant, and it can improve the renal function of patients.