To investigate the effects of moxibustion combined with warming and activating meridian massage for treating blood stasis vessel obstruction type of prolapse of lumbar intervertebral disc, and to analyze its mechanism of action.Methods:A tatal of 160 patients with blood stasis vessel obstruction type of prolapse of lumbar intervertebral disc admitted into the hospital from August 2014 to October 2016 were divided into control group (n＝80) and observation group (n＝80) by drawing lots.Control group received warming and activating meridian massage and observation group received moxibustion on the basis of control group.The changes of scores of TCM symptom, lumbar JOA, VAS, McGill pain questionnaire, ADL, SF-36 questionnaire and the occurrence of adverse reactions of two groups were compared before and after 1-month treatment, and clinical efficacy of two groups were evaluated.Results:One month after treatment, the scores of TCM symptom, VAS, McGill of two groups significantly decreased, while scores of lumbar JOA, ADL, SF-36 significantly increased, and above-mentioned indexes of observation group were better than those of control group (P<0.05); The clinical total effective rate of observation group was 96.25% (77/80), which was significantly higher than 83.75% (67/80) (P<0.05); There was not statistical difference in the total incidence of adverse reactions between the two groups (P>0.05).Conclusion:Moxibustion combined with warming and activating meridian massage in treatment of blood stasis vessel obstruction of prolapse of lumbar intervertebral disc can significantly improve efficacy, relieve clinical symptoms, decrease patients' pain, increase survival quality and not increase the occurrence of adverse actions.It is a kind of safe and reliable treatment method and worthy of clinical generalization.