To evaluate the effect of clinical pharmacists in the intervention of rational use of traditional Chinese medicine (TCM) injection.Methods:According to random number table method, 348 cases of patients were treated with traditional Chinese medicine from March 2015 to March 2016 in our hospital, and they were divided into observational group and control group, each group of 174 cases.The control group was treated with regular Qingkailing injection treatment and the observational group was treated with the clinical pharmacists intervention on the rational use of Qingkailing injection.The unreasonable usage, incidence of adverse reactions, cost per capita, the proportion of the total cost of hospitalization were statistically analyzed in the two groups.Results:The rate of Qingkailing injections unreasonable usage was 25.29% in the control group, and the rate of unreasonable usage was 5.17% in the observational group.The rate of unreasonable usage of the observational group were lower than the control group, and there was statistically different between the two groups (P<0.05); the rate of adverse reactions was 4.60% in the control group, and the rate of adverse reactions was 0.57% in the observational group.There was statistically different between the two groups (P<0.05).The hospital total cost of control group was 9704.8±342.8, and the observational group was 8623.9±298.5.The total cost of Qingkailing injection of control group was 543.5±97.5, and the observational group was 432.2±95.8.There were statistically significant of two groups (P<0.05).Conclusion:The pharmacists intervention can make clinical Chinese medicine injection reasonable, normative, safety.To a certain extent, it can reduce the economic burden of patients, avoid the waste of medical resources, and reduce the rate of adverse reaction incidence and unreasonable utilization.It is obvious that pharmacists intervention plays an important role during the process of the rational use of traditional Chinese medicine injection.