To observe the curative effect of the weizhong (B40) bloodletting puncture in postoperative syndrome of lumbar intervertebral disc protrusion, and simultaneously to discuss the impact on coagulation system. Methods:A total of 90 patients with lumbar intervertebral disc prolapse postoperative syndrome in our hospital from January 2016 to January 2017 were included in the study and randomly divided into control group and the observation group, with 45 cases in each group. The control group had lumbar and abdominal muscles functional training, local hot compress and physiotherapy of physical agents, and the observation group had the weizhong (B40) bloodletting puncture on the basis of the above treatment, once per day. The bleeding volume was controlled in 3 to 5 mL. Both of the two groups had continuous treatment for 10 days. Lumbar pain rating scale (Japanese Orthopaedic Association, JOA), scores changes of modified verbal rating scale (VRS), and the index level changes of coagulation function of two groups before and after treatment were compared. Results:1)After treatment, JOA in the two groups was higher than before treatment, and the differences were with statistically significant (P<0.05). The improvement of observation group were more obviously than the control group in terms of subjective symptoms and signs, and the differences had statistical significance (P<0.05).2)the VRS grading of the two groups were with no significant statistical differences before treatment (P>0.05), and VRS grading of the two groups were both improved after treatment. The improved cases of the observation group was better than that of the control group (P<0.05). 3)The coagulation system indexes of the two groups were obviously improved after treatment, and the observation group was better than that of control group. The differences were with statistically significant (P<0.05). Conclusion:Bloodletting puncture of weizhong (B40) can obviously improve the clinical symptoms and signs of lumbar intervertebral disc prolapse postoperative syndrome, improve the life quality of patients. The mechanism may related to the improving of the blood rheology state in patients.