To observe the clinical curative effect of Renshen Hutao Decoction in the treatment of lung qi deficiency COPD and its effects on the immune system, and to conduct analysis. Methods:A total of 130 COPD patients were randomly selected from January 2015 to January 2017 from inpatients and outpatients in our hospital diagnosed as lung qi deficiency. They were randomly divided into observation group and control group. The control group was treated with the basic treatment of Western medicine, and the observation group was given Renshen Hutao Decoction on the basis of the control group. The pulmonary function, quality of life, T lymphocyte CD3+, CD4+, CD8+, CD19+ content and serum immunoglobulin IgA, IgM, IgG of two groups were compared. Results:After 4 weeks of treatment, the total score of TCM syndrome in the two groups was significantly lower than that before the treatment (P<0.05), and the observation group was better than the control group (P<0.05). The pulmonary function of patients in two groups were significantly improved compared with before treatment (P<0.05). The quality of life and 6 min walking distance was better than before treatment (P<0.05). The levels of CD3+, CD4+, CD4+/CD8+, CD19+, IgA, IgM and IgG all increased significantly, and CD8+ level decreased significantly. Compared with those before treatment, the difference was statistically significant (P<0.05), and the observation group was better than the control group (P<0.05). Conclusion:After application of Renshen Hutao Decoction, clinical symptoms of patients with lung qi deficiency of COPD significantly improved the quality of life, which could stimulate the immune mechanism of patients and improve immunity.