To investigate the influence of yangshen buxin Tang on serum inflammatory factors and myocardial enzyme spectrum of patients with viral myocarditis ( VMC ).Methods:A total of 126 cases of VMC patients in our hospital were selected and divided into the observation group ( n=62 ) and the control group ( n=64 ),according to the different treatment methods.The control group was treated with conventional western medicine treatment,and the observation group was added with yangshen buxin Tang,on the basis of control group.The 2 groups were treated for 2 months.The clinical effects,serum inflammatory factors and myocardial enzyme spectrum indexes levels before and after treatment of the 2 groups were compared and the adverse reaction in the course of treatment of 2 groups were recorded.Results:The total effective rate of observation group and control group after treatment were 90.32% and 75.00% respectively,and the observation group was significantly higher than control group ( P<0.05 ).Compared with those before treatment,the levels of serum IL-6,IL-9,IL-17 and TNF-α of 2 groups after treatment significantly decreased,and observation group was significantly lower than control group ( P<0.01 ).The levels of serum IL-27 of 2 groups after treatment significantly increased,and observation group was significantly higher than control group ( P<0.01 ); compared with before treatment,the levels of serum AST,LDH,CK,CK-MB of 2 groups after treatment significantly decreased,and observation group was significantly lower than control group (P<0.01); the incidence of nausea,vomiting and diarrhea of observation group was significantly lower than those of control group (P<0.05).Conclusion Yangshen buxin decoction in the treatment of VMC patients can effectively reduce the level of serum inflammatory factors and myocardial enzyme spectrum,indexes,improve the clinical curative effect.