To compare the clinical effects of acupuncture and placebo-acupuncture on insomnia and anxiety, and to provide a scientific basis for acupuncture treatment of insomnia and improvement of anxiety and life quality. Methods:A total of 67 subjects with insomnia and anxiety were randomly divided into the experimental group and the control group, and they were randomly divided into experimental group and control group. The experimental group was acupuncture group with 33 cases. The control group was placebo-acupuncture group with 34 cases. Both groups used Park Sham Placebo Acupuncture Device (PSD) needles with acupuncture and placebo-acupuncture. The main points they selected such as Shenmen (HT7), Anmian, Zhaohai (KI6), Shenmai (BL62), Neiguan (PC6), Hegu (LI4), Taichong (LV3) and the dialectical points：Xinshu (BL15), Pishu (BL20), Sanyinjiao (SP6), Danshu (BL19), Taixi (KI3), Xingjian (LV2), Xiaxi (GB43), Fenglong (ST40), Neiting (ST44) were clinically curative after 10 treatments and 1 month and 3 months after treatment. Assessments included Pittsburgh Sleep Quality Index (PSQI), Zung Anxiety Self-Rating Scale (SAS), and acupuncture scales. Results:Compared with PSQI indexes and SAS standard scores after treatment, the acupuncture group was significantly better improved than the placebo-acupuncture group (P<0.05); 1 month after treatment and 3 months after treatment. it was found that PSQI indices and SAS scores rebounded to varying degrees, but the continuous improvement of the acupuncture group was better than that of the placebo-acupuncture group (P<0.05). In the acupuncture scale evaluation, the acupuncture group had a strong sense of needle sensation while the placebo-acupuncture group did not obtain it (P<0.05), and both groups had more sharp pain sensation (P>0.05). Conclusion:Acupuncture and effective of needle sensation can greatly improve the symptoms of insomnia and anxiety of the subjects. The curative effect has a certain downward trend with the passage of time, but it is still better than the placebo-acupuncture group. Acupuncture is an effective means to improve insomnia with anxiety and can greatly improve life quality, which is worthy of attention and promotion.