In recent years, with the changes of ecological environment and social environment, the incidence of digestive tract diseases is increasing year by year, and the scope of application of digestive tract endoscopy is more and more extensive, that could help to observe the tissue structure of cavity which could not be observed by naked eyes, probe into the location of the lesion and improve the disease diagnosis rate. With rapid development of Chinese medicine modernization, the role of traditional Chinese medicine in regulating intestinal dysbacteriosis and promoting the recovery of gastrointestinal function has aroused concern. Particularly, the treatment of endoscopic spraying or injecting of traditional Chinese medicine, proprietary Chinese medicine begins to be used in clinical practice. This study mainly analyzed the application and progress of digestive tract endoscopy combined with traditional Chinese medicine in digestive tract diseases.