To systematically review the hospital mortality rate of patients with acute myocardial infarction (AMI) in China from 2001 to 2017.Methods:By searching Wanfang database，CNKI，VIP database and PubMed，and screening according to inclusion and exclusion criteria，a systematic review was conducted on the 32 articles that were finally included with 1 000 subjects or more.The Meta-Analyst software was applied to calculate the overall hospital mortality rate and 95% confidence interval，and the forest map was drawn to analyze the distribution of gender，age，time and region.Results:Based on the data reported in the literature，the crude fatality rate of hospitalized patients with AMI was 8.5%，and that of male and female patients was 8.0% and 12.1%，respectively.According to the age distribution，the case fatality rate of people over 80 years old reached 30%.Compared with 13.1% of people aged 60-79 years old，the case fatality rate of people aged 20～39 years old and 40～59 years old was 4.3%.According to the regional distribution，the case fatality rate (19.1%) in southwest China and 15.3% in northwest China was significantly higher than that in other regions (8.8% in north China，7.0% in northeast China，7.7% in eastern China，6.8% in central south and 9.6% in south China).According to the time distribution，the crude case fatality rate (10.3%) in 2006-2011 was significantly higher than that in 2000-2005 (7.8%) and 2012-2017 (6.8%).Conclusion:The mortality rate of hospitalized patients with AMI is still high in China，and the strategy of prevention and treatment of acute myocardial infarction is worthy of further study.