To study the effects of Jiawei Simiao Pill with Western medicine on the symptoms of joint swelling and pain and blood biochemical indexes in patients with acute gouty arthritis.Methods:A total of 60 cases of acute gouty arthritis who were admitted to our hospital from January 2014 to January 2017 were selected and randomly divided into study group and control group,with 30 cases in each group.The control group was treated with Diclofenac Sodium Sustained Release Tablets and Sodium Bicarbonate Tablets,while the study group was additionally treated with the Jiawei Simiao Pill with the course of 3 days.The clinical effects of 2 groups,the symptoms of joint swelling and pain and the changes of blood biochemical indexes before and after 3 days treatment were compared,and the occurrence of adverse reactions was observed.Results:The total effective rate of treatment in the study group was 96.67%,which was significantly higher than 80.00% of the control group(P<0.05).After the treatment of 3 d,the joint pain score,joint pressure pain score and joint swelling score of 2 groups were decreased significantly,and the study group was lower than that of the control group(P<0.05).After the treatment of 3 d,the blood uric acid,erythrocyte sedimentation rate and C reactive protein(CRP)in the 2 groups were significantly decreased,and the study group was lower than that of the control group(P<0.05).There were no significant differences in the incidence of dizziness,nausea,vomiting and diarrhea between the study group and the control group(P>0.05).Conclusion:Jiawei Simiao Pill with western medicine in the treatment of acute gouty arthritis has obvious curative effects,and effectively improve the symptoms of joint swelling and pain and the level of blood uric acid and erythrocyte sedimentation rate.It is safe and worthy of clinical application.