Insomnia is a common clinical disease.The incidence rate is high in modern society.It is caused by mental and emotional factors,and many patients suffer greatly from life and work.Due to the obvious side effects of long-term use of western medicine,traditional Chinese medicine treatment has certain advantages.Professor Liu Qingquan explained the pathogenesis of insomnia from the spleen cold pathogenesis,and the treatment was effective with the modification of Chaihu Guizhi Ganjiang Decoction,Danzhi Xiaoyao Powder,Xuefu Zhuyu Decoction and Yiqi Congming Decoction.This paper introduced 4 related medical cases.