To observe the clinical efficacy of and comparatively analyze the effect of intra-articular sodium hyaluronate injection in the ankle and Chinese herbal medicine soaking in the treatment of TakakuraⅠankle osteoarthritis.Methods:A total of 55 patients with TakakuraⅠankle osteoarthritis admitted in Department of Orthopedics,Dongzhimen Hospital and Bayannaoer City Hospital from July 2016 to December 2017 were retrospectively analyzed.According to different treatment methods,patients were divided into observation group (n＝25) and control group (n＝30).The observation group was treated with Chinese herbal medicine soaking and the control group was treated with intra-articular sodium hyaluronate injection.The degree of joint pain and swelling,joint mobility (ROM) and American Association of Orthopedic Surgeons ankle and hindfoot score (AOFAS) of the two groups before and after one month of treatment were observed,and the differences between the two groups were analyzed.Results:There was no significant difference in pain scores,swelling scores,joint mobility and AOFAS scores between the two groups before treatment (P>0.05).The scores of joint swelling and pain in the two groups were better than those before treatment.The pain scores of the joint cavity injection group was better than that of the Chinese herbal medicine soaking group (P<0.05),and the swelling scores was not significantly different (P>0.05).The scores of ROM and AOFAS in the two groups were better than those before the treatment,and there was no significant difference in the ROM scores between the two groups (P>0.05).The AOFAS scores in the joint cavity injecting group was better than that of the Chinese herbal medicine soaking group (P<0.05).Conclusion:Chinese herbal medicine soaking and intra-articular sodium hyaluronate injection in the ankle can achieve good clinical results.The intra-articular injection has better analgesic effect and better effect in improving ankle joint function.