To discuss the effects of Wenyang Huoxue Decoction on inflammatory factor in patients with stable chronic obstructive pulmonary disease (COPD) with syndrome of yang deficiency of spleen and kidney.Methods:A total of 158 patients with COPD were selected from January 2016 to January 2017 in Qinghai Provincial People's Hospital,and were divided into observation group and control group according to the random number table method,with 79 cases in each group.Patients in the two groups were both given symbicort turbuhaler for treatment,and Wenyang Huoxue Decoction was added in the observation group．Changes in scores of revised pulmonary function parameters and inflammatory factor in every group were observed in baseline phase and after treatment (2 months after treatment).Results:In baseline phase,pulmonary function parameters and inflammatory factor of two groups were basically the same,and there was no statistically significant difference (P>0.05).After treatment,PEFR,FEV1 and FEV1/FVC in the observation group were higher than those of the control group,which were statistically significant (P<0.05).IL-6,IL-8 and TNF-α in the observation group were lower than those of the control group,which were statistically significant (P<0.05).Conclusion:Symbicort turbuhaler combined with Wenyang Huoxue Decoction has good effects on treating stable chronic obstructive pulmonary disease with syndrome of yang deficiency of spleen and kidney.Mechanism may be associated with reducing patients' serum levels of IL-6,IL-8 and TNF-α.