To compare the clinical efficacy of different dosages of Xiaojin Capsule (0.35 g/capsule) in the treatment of thyroid nodule and breast hyperplasia.Methods:This study was designed using the prospective study.All cases that conformed to the inclusion and exclusion standard were competitively included from the same agreed time.The 300 thyroid nodule cases (six-month follow-up,main indicators were TCM symptom improvement and nodule narrowing) and 500 breast hyperplasia cases (three-month follow-up,main indicators were breast pain relief and hyperplasia shrinking) from 15 hospitals of grade B class 3 and over from May 2014 to August 2016 were selected to join the investigation.Results:A total of 353 thyroid nodule cases and a total of 498 breast hyperplasia cases completed the study.The thyroid nodule cases were divided into three layers based on gender,age,and smoking amount factors.The breast hyperplasia cases were divided into four layers based on age and fertility number factors.In thyroid nodule cases,dosage of 5-6 capsules per time achieved 100% efficient,and dosage of 4 capsules per time achieved >88% efficient.In breast hyperplasia cases,dosage of 5-6 capsules per time achieved 100% pain symptom efficient,and dosage of 4 capsules per time achieved >85% efficient.Conclusion:Dosage of 4 capsules per time of Xiaojin Capsule may obtain good curative effect and is relatively economic for both thyroid nodule and breast hyperplasia treatment.Furthermore,dosage increase may appropriately increase the curative effect with no adverse drug reaction.