This paper summarized the sweat pore theory elucidated by the past dynasties doctor and some points of sweat pore theory application，and based on which，combined general theory of sweat pore with tutor clinical experience，brought out that most of chronic urticaria is caused by the disordered defensive energy，the abnormal function of sweat pore and the pathogenic wind attacking from the exterior，leading to the closed sweat pore.The pathogenesis of the disease is the closure of sweat pores，thus the treatment should simultaneously base on elimination and reinforcement，pay attention to the condition of the location of the disease instead of the cold and heat，open the sweat pores and resuscitate to smooth the circulation of qi and body fluid.