To investigate clinical effects of Yiqi Yangxin Formula combined with Danshen injections in the treatment of patients with chronic obstructive pulmonary disease(COPD)and pneumocardial disease.Methods:A retrospective analysis was performed on 68 patients with COPD complicated with pneumocardial disease treated in our hospital from September 2015 to July 2016.The 68 patients were randomly divided into experimental group and control group with 34 cases in each group according to the sequence of treatment.Patients in control group were treated with intravenous injection of Mailuoning based on conventional treatment.The patients in the experimental group were treated with Yiqi Yangxin Formula combined with Danshen injections based on conventional treatment.The improvement of final curative effects and the changes of pulmonary function,blood gas index,blood coagulation and fibrinolysis of 2 groups were compared.Results:After treatment,the curative effects of experimental group were significantly higher than that of control group(P<0.05).After the course of treatment,the forced expiratory volume in 1 s(FEV1),forced vital capacity(FVC),peak expiratory flow(PEF)and maximum voluntary ventilation(MVV)were significantly improved compared with that before treatment,and the experimental group was significantly higher than that of control group(P<0.05).There was no significant difference in PH value between 2 groups(P>0.05).The partial pressure of oxygen(PaO2)in experimental group was higher than that of the control group,and the PaCO2 of experimental group was lower than that of control group(P<0.05).The prothrombin time(PT)and thrombin time(TT)in the experimental group were significantly higher than that of control group,while fibrin(FIB)indicators lower than the control group(P<0.05),and platelet count(PLT)showed no significant difference(P>0.05).No serious adverse events occurred during hospitalization in all patients.Conclusion:The treatment of COPD combined with pneumocardial disease with Yiqi Yangxin Formula and Danshen injections has significant curative effects.It can effectively optimize the pulmonary function,blood gas index,hemagglutination and fibrinolysis indexes of patients with COPD and quickly relieve the clinical symptoms without serious adverse reactions,which has the promotion and application value.