To analyze the effects of the method of regulating qi and descending turbid substance to harmonize stomach on treating nonerosive reflux disease.Methods:From October 2017 to March 2018 in Changzhou Traditional Chinese Medicine Hospital，a total of 100 patients with nonerosive reflux disease were divided into control group (n=50) and observation group (n=50).The control group was treated with rabeprazole，and the observation group was given traditional Chinese medicine.Traditional Chinese Medicine (TCM) symptom scores，adverse reaction，recurrence rate of two groups were compared.Results:After treatment，the total effective rate of the observation group was 92%，which was significantly higher than 76% of the control group.After treatment，TCM symptom score of two groups was significantly decreased，and the score of the observation group was significantly lower than that of the control group.Two groups had no obvious adverse reactions.In the treatment of belching and upper abdominal distention，the curative effect of the observation group was significantly better than that of the control group.In the following-up period after two weeks of treatment，the recurrence rate of cured patients in the observation group was significantly lower than that in the control group.Conclusion:The method of regulating qi and descending turbid substance to harmonize stomach can effectively treat nonerosive reflux disease.