As the morbidity rate of gout increase significantly year by year，the refractory and the recurrent nature of gout has become the main problems and difficulty in clinical treatment.Currently，the application of anti-gout western medicine results effectively in inflammation controlling and uric acid reduction.However，the long-term application might lead to many adverse reactions.Glabrous Greenbrier Rhizome，as a kind of common traditional Chinese medicine，has remarkable effects in clinical treatment of gout，with little side effects.This paper reviewed some progresses on chemical constituents and anti-gout mechanism of Glabrous Greenbrier Rhizome，aiming at providing references for its research and development into anti-gout drugs.