To discuss the effects of Compound Qianggu Decoction on the healing degree and bone metabolism of patients with osteoporotic vertebral compressibility fracture (OVCF). Methods:A total of 100 patients with OVCF were selected from June 2013 and June 2016 in Shantou Hospital of Traditional Chinese Medicine. According to the treatment，all patients were divided into Compound Qianggu Decoction group (50 cases) and control group (50 cases). All patients were treated with percutaneous vertebroplasty (PVP)，and control group was given calcium carbonate D3 tablets，on the basis of which Compound Qianggu Decoction group was given Compound Qianggu Decoction. Results:Serum alkaline phosphatase (ALP)，urinary deoxypyridine (DPD) level and pain visual analogue scoring (VAS) scores in the Compound Qianggu Decoction group and control group were significantly decreased after treatment，and those of Compound Qianggu Decoction group after treatment were significantly lower than those of the control group. The density of lumbar L1-4，large tuberosity and height of Cobb Angle and vertebral anterior border were significantly increased after treatment，and those of Compound Qianggu Decoction group were statistically significantly higher than those of the control group (P<0.05). During the 12-month follow-up period，the recurrence rate of bone fracture of redistributed vertebral body in Compound Qianggu Decoction group was significantly lower than that in the control group，and the difference was statistically significant (P<0.05). Conclusion:The treatment of Compound Qianggu Decoction can effectively improve bone metabolism and bone density in OVCF patients，and it is helpful to alleviate pain and promote healing of fracture，and it can reduce the risk of vertebral fracture effectively，which is worthy of further clinical promotion.