To study the effects of Yiqi Huoxue Prescription combined with triple therapy on inflammatory reaction and hemorheology in patients with Qi deficiency and blood stasis type chronic atrophic gastritis (CAG).Methods:A total of 160 patients with Qi deficiency and blood stasis type CAG who were treated in Xinxiang Central Hospital from January 2016 to December 2017 were included in the study.According to the random number table method, the patients were divided into the observation group and the control group with 80 cases in each group.The control group was treated with triple therapy of omeprazole, amoxicillin and clarithromycin.The patients in the observation group were combined with Yiqi Huoxue prescription on the basis of control group, and two groups were treated for 8 weeks.The clinical efficacy, the improvement of clinical symptoms and the incidence of adverse reactions were compared between the two groups, and the levels of inflammatory factors and hemorheology were compared before treatment and 8 weeks after treatment.Results:The total effective rate of the observation group was 95.00%, which was significantly higher than the control group of 85.00% (P<0.05).The total improvement rate of fullness, stomachache, aversion, belching, fatigue, upper abdominal tenderness and tongue appearance in the observation group were all higher than those of the control group (P<0.05).After treatment, the levels of interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), epidermal growth factor (EGF), interleukin-32 (IL-32) and transforming growth factor-β1 (TGF-β1) in the observation group were significantly lower than the control group, and the levels of plasma viscosity, whole blood viscosity, erythrocyte sedimentation rate and fibrinogen were also significantly lower than those in the control group (P<0.05).The total incidence of adverse reactions in the observation group was 5.00%, compared with 8.75% in the control group, and the difference was no statistical significance (P>0.05).Conclusion:The treatment of patients with qi deficiency and blood stasis type of CAG with Yiqi Huoxue Prescription combined with triple therapy is safe and effective.It can also improve the inflammatory reaction and hemorheology of the body and help to improve the recovery of patients.